Genetics
Full course description
The course discusses the principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. The topics include: structure and function of genes; chromosomes and genomes; biological variation resulting from replication and recombination, mutation and selection; DNA repair and the genetic basis of disease inheritance.
Course objectives
- To understand the chemical structure of DNA and the molecular mechanisms of DNA replication.
- To get familiar with the basic principles how information stored in genes is converted to a (cellular) phenotype in the form of RNA and protein.
- To understand the molecular basis of single and multiple gene inheritance (Mendel’s laws), sex-linked single gene inheritance, complex genetic conditions, and to interpret human pedigrees.
- To have sufficient background for more advanced courses in biochemistry and the life sciences.
Prerequisites
- BIO2001
Co-requisites
- PRA2014
Recommended reading
“Introduction to Genetic Analysis” by Griffiths, Wessler, Carrol, Doebley (Palgrave Macmillan, 12th edition, 2020. ISBN-13: 9781319114770).
BIO2007
Period 1
2 Sep 2024
25 Oct 2024
Period 4
3 Feb 2025
4 Apr 2025
ECTS credits:
5.0Instruction language:
EnglishCoordinator:
Teaching methods:
Lecture(s), PBLAssessment methods:
Attendance, Written exam, Participation, Presentation