Genetics
Volledige vakbeschrijving
The course discusses the principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. The topics include: structure and function of genes; chromosomes and genomes; biological variation resulting from recombination, mutation and selection; DNA repair and the genetic basis of disease inheritance; and evolutionary genetics.Doelstellingen van dit vak
• To understand the chemical structure of DNA and the molecular mechanisms of DNA replication. • To get familiar with the basic principles how information stored in genes is converted to a (cellular) phenotype in the form of RNA and protein. • To comprehend and be able to apply the concepts of genome structure, comparative genomics, and functional genomics. • To understand the molecular basis of single gene inheritance (Mendel’s first law), sex-linked single gene inheritance and to interpret human pedigrees. • To use the above information to deduce the concepts of Darwin’s theory of Natural Selection, molecular evolution and the origin of new genes and species. • To have sufficient background for more advanced courses in biochemistry and the life sciences.Voorwaarden
Pre-requisites BIO2001 Cell Biology Co-requisites PRA2014 Skills GeneticsAanbevolen literatuur
"Introduction to Genetic Analysis" by Griffiths, Wessler, Carrol, Doebley (W.H. Freeman, 10thedition, International Edition, 2012. bol.com price €64,99).BIO2007
Periode 1
2 sep 2024
25 okt 2024
Periode 4
3 feb 2025
4 apr 2025
Studiepunten:
5.0Taal van de opleiding:
EngelsCoördinator:
Onderwijsmethode:
Lecture(s), PBLEvaluatiemethoden:
Attendance, Written exam, Participation, Assignment