Practical Training: Immunocytochemical Staining of Human Postmortem Tissue and Evaluation of the Staining Using the Multihead Microscope

Doelstellingen van dit vak

Students will be able to understand:

• collecting Postmortem tissue, fixation, paraffin, immunocytochemical staining, recognition of neuropathological hallmarks in Tauopathies: Alzheimer’s disease (AD);
• plaques, tangles;
• early and late onset AD, Amyloid beta cascade hypothesis, amyloid precursor protein, Tau, ubiquitin, GFAP, gliosis, cytoarchitecture of hippocampus and neocortex.