Nutritional Pharmacotherapy
Full course description
The course will start with an introduction on the role of reactive oxygen species (ROS) and oxidative stress in (chronic) disease. Subsequently, pharmacotherapeutical options for various diseases like cardiovascular diseases (hypertension, heart failure), lung diseases (asthma, COPD) and diabetes will be discussed. Furthermore, during this course the adaptive response in cells, inducing either repair mechanisms or enhanced protection after exposure to (low) doses of a toxicant will be investigated. In all these processes the role of nutrition and nutritional components (e.g. food supplements) on the efficacy and safety of the pharmacotherapy will be the common thread running through the course.
Course objectives
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To provide general knowledge on pharmacotherapy for various diseases.
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To give insight in the possibilities to optimize pharmacotherapy with dietary components (nutrition) and food supplements.
Prerequisites
- VSC2103 Pharmacology and Toxicology
Recommendations: VSC2104 Molecular Biology
Recommended reading
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B. Halliwell and J.M.C. Gutteridge. Free Radicals in Biology and Medicine, 5th Edition. Oxford University Press (2015);
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A. Bast and J.C. Hanekamp. Toxicology: What Everyone Should Know: A Book for Researchers, Consumers, Journalists and Politicians. Academic Press, Elsevier (2017);
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H. P. Rang, J. M. Ritter, R. J. Flower, and G. Henderson. Rang and Dale’s Pharmacology, 8th Edition. Churchill Livingstone, Elsevier (2015);
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Original research articles.