Scientific Methods and Analytics
Full course description
After graduation, you will have to translate and communicate industrial- and consumer relevant questions into innovative scientific research questions, and interpret scientific results for the benefit of product development. This requires thorough insight in the skills which are needed to design, conduct and understand experiments in nutritional sciences. Accordingly, this course is designed to train you in the methodology of scientific (specifically nutritional) studies, and provide you with knowledge on a number of analytical techniques and practical skills, which are essential to conduct scientific intervention trials for the substantiation of for example product benefit claims. A broad view with attention to in vivo, ex vivo and in vitro technologies will be offered. Special attention will be given to epidemiological research. Epidemiology is an important scientific discipline, especially in an industrial setting, where often the methodology and facilities are lacking to conduct large-scale interventions. In this course, we will discuss descriptive epidemiology and develop the skills to find, critically read and judge the quality of scientific literature. All activities will be supported by problem cases, which will be discussed in Problem Based Learning groups. On each of the different topics which are covered, lectures will be provided by academic staff.
Course objectives
- Comprehension of the etiology of- and patho-biological theories (and research behind these theories) of chronic metabolic disorders in which lifestyle and diet play a significant role
- Comprehension of the role of epidemiology in assessing “Diet-Health” relationships;
- Understanding public health and risk/benefit assessment (incl. toxicology aspects);
- Insight in clinical trial design and its role related to impact on the degree of health benefit evidence;
- Insight in the design and role of meta-analyses and reviews;
- Have in idea about what research integrity (and FAIR) means in nutritional science
Recommended reading
- • Original recent research articles that will be referred to in the syllabus. • Original research articles and reviews on relevant topics, to be collected on own initiative, according to training 'how to find and interpret scientific literature'.
- F.H.M. van Osch