Immunology
Full course description
The immune system of vertebrates exists of a collection of cells, tissues and molecules that mediate resistance to foreign intruders. These intruders (e.g. pathogenic microorganisms) can be seen as the enemy and the immune system as the defense system. Microorganisms can enter the body through the airways, the gastro-intestinal tract, the urogenital tract, and through damaged skin. The invaders usually have the capacity to multiply fast and overgrow the host in a short period of time. Fortunately, the immune system is able to destroy or restrain the intruders, or to neutralize the toxic substances the intruders produce. The course focuses on the role of different humoral factors, cells and cell systems of the innate and adaptive immune system, that are involved in the defense of an organism against these intruders. In addition, the processes involved in immunization, allergy, vaccination and transplantation will be discussed.
Course objectives
- To gain knowledge and insight in cells and humoral factors of the innate and adaptive immune system.
- To gain knowledge and insight in cellular and molecular effector mechanisms of the innate and adaptive immunity during inflammation and infection.
- To gain knowledge and insight in the structure and function of primary and secondary lymphoid tissue.
- To gain knowledge and insight in the processes in the immune response after immunization and vaccination.
- To gain knowledge and insight in immune mechanisms in disease.
Prerequisites
SCI1009 Introduction to Biology. Students with substantial high school experience in biology (for an indication of the relevant topics, see SCI-B, p. vi-viii) can contact the coordinators to request a waiver.
Recommended
SCI2037 Cell Biology, SCI2040 Microbiology.
Recommended reading
- Abbas, A.K., Lichtman A.H. and Pillai, S. (2023). Basic Immunology (7th ed.). Philadelphia: Elsevier.