Engineering the Immune System; Treatment of Disease
Volledige vakbeschrijving
Building on the knowledge gained by the student in the MBS1201 course, the MBS1202 course will follow roughly the same roadmap through the various areas of research and clinical medicine, covering immunology, inflammation and the pathophysiology of infectious and non-infectious diseases with a focus on therapy. Attention will be given to approaches and technologies in the field of experimental medicine as well as the more general translational aspects related to the topics relevant to the areas of sterile and nonsterile (infectious) inflammation, neurodegeneration, atherosclerosis and vascular disease, autoimmunity and tumor development.
The objective of this course is to provide a basic understanding of various important techniques and technologies in this field and create an awareness of experimental and approved methods for the treatment of immune-related diseases.
Doelstellingen van dit vak
- Summarize, explain and design approaches to modulate the immune system in inflammatory or infectious disease
- Summarize and explain basic pathophysiology, diagnosis and current therapy of sepsis and design novel therapeutic strategies
- Summarize and explain basic pathogenesis and current treatment of viral disease and design novel prophylactic vaccine based strategies for viral disease
- Explain and compare current and experimental therapies to treat/prevent atherosclerosis
- Explain and compare established and experimental types of immunotherapy and design novel therapeutic strategies
- Summarize state of the art diagnosis and treatment of hypersensitivity disorders
- Explain the therapeutic potential of targeting the microbiome for modulation of immunity and health
- Apply both descriptive ethics and normative ethics to a case study relevant within the specialisation