Non-invasive Neuromodulation
Volledige vakbeschrijving
This course will explore various state-of-the-art non-invasive neuromodulation approaches in detail, with a particular focus on transcranial magnetic and electrical stimulation (TMS/TES). In addition, the course showcases how insights into the pathophysiology of the central nervous system can be translated into clinical applications of non-invasive neuromodulation in psychiatry, neurology, and neuro-rehabilitation. Prominent examples include the application of TMS in depression and stroke. These and many other examples will be discussed, revealing the potential of non-invasive neuromodulation in clinical practice. At the end of this course, students will have a proper understanding of current non-invasive neuromodulation techniques and they will be aware of recent trends and developments for both fundamental and clinical applications.
Doelstellingen van dit vak
Intended Learning Outcomes (ILO) in this course:
ILO1601-1: To understand the basic mechanisms of action of transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (TES)
- To describe the physical foundation of TMS and TES
- To describe the physiological consequences of TMS and TES protocols
- To describe, explain, and compare commonly used TMS and TES protocols
ILO1601-2: To understand how TMS and TES can be applied in experimental context
- To determine and discuss which TMS and TES protocols are suitable to addressing different research questions
- To interpret outcomes of TMS and TES experiments
- To gain practical, hands-on knowledge and experience with TMS and TES, including procedural and safety considerations
ILO1602-3: To know about cutting-edge developments and future perspectives of non-invasive neuromodulation
- To know about advanced concepts of non-invasive neuromodulation
- To discuss current limitations of the field and identify ways forward
- To integrate acquired knowledge and skills to reflect on novel applications of non-invasive neuromodulation
ILO1601-4: To describe the current neuroimaging techniques available for neuromodulation.
- To discuss how neuroimaging can be applied to improve targeting in neuromodulation
- To gain practical experience in pre-processing fMRI and EEG data in the context of a multimodal NIBS experiment
- To describe the state of the art in novel research and clinical applications of multimodal NIBS
ILO1602-5: To describe and discuss the applications of TMS in psychiatry
- To know about the pathophysiology of depression
- To explain current treatment approaches in psychiatry with TMS
- To gain practical, hands-on knowledge and experience with the implementation of a TMS treatment session
ILO1602-6: To describe and discuss the applications of TMS in neurology and neurorehabilitation
- To understand the use of TMS as a diagnostic and prognostic tool
- To explain current treatment approaches in neuro-rehabilitation with TMS
- To gain practical, hands-on knowledge and experience with the combination of TMS and electromyographic recordings
Aanbevolen literatuur
This course almost exclusively relies on recent scientific articles published in international peer-reviewed journals. On rare occasions, a text book may be used to provide basic knowledge required for a topic.
- H.P. Leunissen