Non-invasive Techniques in Biomedical Research
Volledige vakbeschrijving
Imaging is a crucial step to visualize and conceptualize important processes in health and disease on various scales, ranging from molecular detail, via cellular and tissue level, towards animal and patient. In this 4-weeks course various invasive and non-invasive imaging techniques, frequently used in both research and clinic, will be introduced and discussed. These techniques are advanced optical microscopy, MS Imaging, MRI/MRS, PET/CT, and Breath/faeces analysis.
Combining lectures, practicals, and dedicated tutorials, in the first two weeks all the mentioned imaging methods will be introduced in general terms. After these two weeks, the group will be divided over five topics (MRI/MRS; PET/CT; MSI; B/F analysis; and Optical Microscopy). The topic will, within this group, be discussed in more detail. During weeks 1 to 4 the students will work on writing an Imfolio individually, containing up-to-date information on the practicals of each week.
While each group during the last 2 weeks will go into details on one topic only, the general line of imaging methods will come back in the final assignment. Subgroups (e.g., half the tutor groups) will work on the assignment from the start of the block. They will defend their (group) assignment at the end of the block in to other sub groups. Both defense and asking questions to other sub groups will be graded, including self-assessment.
Doelstellingen van dit vak
B-ILO-1: Students learn the difference between various non-invasive imaging techniques.
B-ILO-2: Students can select and apply the best (combination of) methods to a specific question in ether clinical or research setting.
B-ILO-3: Students can deal with complex data in a practical setting.
B-ILO-4: Students have in-depth knowledge on one of the following techniques:
- Optical Microscopy
- Mass Spectroscopic Imaging
- MRI/MRS
- PET/CT
- Breath and Faeces analysis
Aanbevolen literatuur
- L.J. Dubois
- B.D. Balluff