From Cradle to Grave: Development, Ageing and Disease

Fac. Health, Medicine and Life Sciences

From Cradle to Grave: Development, Ageing and Disease

Volledige vakbeschrijving

This course is dedicated to post-natal development, ageing and development of (age related) disease. Aspects of the respiratory and musculoskeletal systems, as well as sexual development, motor development and brain maturation and cognitive development will be explained at the molecular, cellular and functional level. At the other side of the spectrum of ‘living’, human ageing and the associated functional decline of various systems will be illustrated. In addition, during the course risk factors (genetic, lifestyle, environment) that affect development, ageing and (ageing related) disease will be discussed. In parallel the SoPhiA longitudinal track will be teached during this period (BBS2008-part I). Sophia focuses on normative aspects of prevention of (later onset)) disease, which are linked to the content of the course BBS2002.

Doelstellingen van dit vak

B-ILO2002.1 Describe post-natal development

  1. Describe physical growth (muscle and bone) and sexual maturation 
  2. Describe the effect of hormones on physical growth and sexual maturation
  3. Describe the post-natal development of the organ systems such as lung and brain on cellular, structural and functional level

B-ILO2002.2 Describe the ageing process, explain its underlying biological mechanisms and functional consequences

  1. Describe the evolutionary theories of ageing and use them to explain the ageing process
  2. Describe maintenance and repair mechanisms and explain how homeostasis changes with ageing
  3. Describe the hallmarks of ageing (molecular and cellular) and use them to explain the ageing process
  4. Explain the functional consequences of ageing with respect to muscle and bone, brain, organ systems and immune system

B-ILO2002.3 Describe the pathogenesis and explain risk factors of specific age related diseases

  1. Explain the interplay between stem cells, stress, ageing and disease such as cancer.
  2. Describe age related diseases (such as neurodegenerative disease, lung disease, musculoskeletal decline) and explain the relationship with the hallmarks of ageing.
  3. Explain risk factors of specific age related diseases
  4. Explain potential interventions to support healthy ageing

B-ILO2002.4 Explain the effect of genetics, lifestyle and environmental factors in post-natal development, the ageing process and the pathogenesis of age related diseases

Aanbevolen literatuur

This is the link to Keylinks, our online reference list.  

BBS2002
Periode 2
28 okt 2024
20 dec 2024
Vakbeschrijving afdrukken
Studiepunten: 
6.0
Taal van de opleiding: 
Engels
Coordinators:
Onderwijsmethode: 
Assignment(s), Lecture(s), Work in subgroups, Paper(s), PBL, Presentation(s), Skills, Training(s)
Evaluatiemethoden: 
Assignment, Attendance, Final paper, Participation, Presentation, Written exam, Computertest